Methods for leveraging social media data to quantify and improve pharmacovigilance efforts

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Abstract/Contents

Abstract
Adverse drug reactions impact the health of 100,000s of individuals annually in the United States with associated costs in the hundreds of billions. Pharmacovigilance seeks to improve drug safety and limit patient potential for adverse drug events. Social media has been identified as a promising potential source of information for pharmacovigilance. The adoption of social media data as a component of pharmacovigilance efforts has been hindered by the massive and noisy nature of the data. I present work seeking to (1) identify social media data discussions of drug and drug-related terms, (2) use word embeddings derived from social media data to create quantitative severity scores for adverse drug reactions, and (3) create digital cohorts of social media users and monitor them for changes in prevalence of drug discussion rates in the general US potential, specifically with regards opioids. I present novel methods that enabled these efforts, as well as the results and findings of these efforts. I believe leveraging social media data to enhance pharmacovigilance will benefit U.S. patient populations and further empower public health and regulatory efforts

Description

Type of resource text
Form electronic resource; remote; computer; online resource
Extent 1 online resource
Place California
Place [Stanford, California]
Publisher [Stanford University]
Copyright date 2021; ©2021
Publication date 2021; 2021
Issuance monographic
Language English

Creators/Contributors

Author Lavertu, Adam Allen Joseph
Degree supervisor Altman, Russ
Thesis advisor Altman, Russ
Thesis advisor Chen, Jonathan H
Thesis advisor Eichstaedt, Johannes C
Thesis advisor Liang, Percy
Degree committee member Chen, Jonathan H
Degree committee member Eichstaedt, Johannes C
Degree committee member Liang, Percy
Associated with Stanford University, School of Medicine, Department of Biomedical Data Science

Subjects

Genre Theses
Genre Text

Bibliographic information

Statement of responsibility Adam Lavertu
Note Submitted to the Department of Biomedical Data Science
Thesis Thesis Ph.D. Stanford University 2021
Location https://purl.stanford.edu/zv853wv3862

Access conditions

Copyright
© 2021 by Adam Allen Joseph Lavertu
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

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