Integration and measurement for building synthetic cells

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Abstract/Contents

Abstract
Integration--combining the many cell-essential molecular functions such that they work together--is the key challenge is building a functioning synthetic cell. In order to integrate, we must be able to measure multiple genetic circuits and molecular components working together, in the same cell, at the same time. We have prototyped a platform for integration, using cryo-electron microscopy to visualize individual synthetic cells operating integrated molecular modules, quantifying the synthetic cells and molecules within them, and characterizing their performance.

Description

Type of resource text
Form electronic resource; remote; computer; online resource
Extent 1 online resource.
Place California
Place [Stanford, California]
Publisher [Stanford University]
Copyright date 2023; ©2023
Publication date 2023; 2023
Issuance monographic
Language English

Creators/Contributors

Author Jackson-Smith, Anton Charles
Degree supervisor Endy, Drew
Thesis advisor Endy, Drew
Thesis advisor Chiu, Wah
Thesis advisor Salit, Marc
Degree committee member Chiu, Wah
Degree committee member Salit, Marc
Associated with Stanford University, School of Engineering
Associated with Stanford University, Department of Bioengineering

Subjects

Genre Theses
Genre Text

Bibliographic information

Statement of responsibility Anton Jackson-Smith.
Note Submitted to the Department of Bioengineering.
Thesis Thesis Ph.D. Stanford University 2023.
Location https://purl.stanford.edu/yt728jc2185

Access conditions

Copyright
© 2023 by Anton Charles Jackson-Smith
License
This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).

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