Modern theory of protein folding
Abstract/Contents
- Abstract
- Despite over half a century of study, many interesting questions concerning protein folding remain. I detail the gaps in our theoretical understanding of folding, describe how new theories and experiments could fill those gaps, and discuss my own attempts to understand one of biology's most amazing phenomena. Specifically, I discuss how master equations can be used to understand folding kinetics, how we can understand the surprising simplicity of folding kinetics, and how a experiments determining the rate-length law of folding could contribute to our ability to falsify theoretical arguments. I conclude with five stimulating questions that if answered would further our understanding of folding significantly.
Description
Type of resource | text |
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Form | electronic; electronic resource; remote |
Extent | 1 online resource. |
Publication date | 2015 |
Issuance | monographic |
Language | English |
Creators/Contributors
Associated with | Lane, Thomas Joseph |
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Associated with | Stanford University, Department of Chemistry. |
Primary advisor | Pande, Vijay |
Thesis advisor | Pande, Vijay |
Thesis advisor | Das, Rhiju |
Thesis advisor | Markland, Thomas E |
Advisor | Das, Rhiju |
Advisor | Markland, Thomas E |
Subjects
Genre | Theses |
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Bibliographic information
Statement of responsibility | Thomas J. Lane. |
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Note | Submitted to the Department of Chemistry. |
Thesis | Thesis (Ph.D.)--Stanford University, 2015. |
Location | electronic resource |
Access conditions
- Copyright
- © 2015 by Thomas Joseph Lane
- License
- This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).
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