Prior-knowledge-based optimization approaches for CT metal artifact reduction

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Abstract/Contents

Abstract
The steak artifacts caused by metal implants have long been recognized as a problem that limits various applications of computed tomography (CT). This type of artifacts typically occurs from metallic implants like dental fillings, hip prostheses, implanted marker bins and branchy-therapy seeds. The artifacts not only blur the CT images and lead to inaccuracies in diagnosis, but also make delineation of anatomical structures intractable, which is important in image-guided intervention procedures. This dissertation focuses on utilizing prior knowledge wisely to reconstruct artifact-reduced high-quality images. Several optimization approaches that integrate prior knowledge in both image and projection spaces are proposed. First, we propose a constrained optimization model that features an anisotropically penalized smoothness objective function, subject to a data tolerance constraint and an image non-negativity constraint. Numerical examples and experimental examples are presented to demonstrate that the algorithm is capable of significantly reducing metal streak artifacts, suppressing noise and preserving edge structures. Second, a sequentially reweighted TV minimization algorithm is proposed to fully exploit the sparseness of image gradient (IG). This approach, by altering a single parameter in the weighting function, flexibly controls the sparsity of IG and reconstructs artifacts-free images in a two-stage process: binary reconstruction and background reconstruction. It is therefore a systematic approach that first identifies metal traces from projection space and then reconstructs metal-free image based on metal-trace-removed projection data. Finally, we propose a projection in-painting method that takes advantage of the piece-wise smoothness of projection data. A penalized-least-squares (PLS) model is used to obtain a smoothed projection image that realistically represents the ideal noise-free projection. Experimental phantom studies and clinical examples are presented to demonstrate the performance of the proposed in-painting algorithm.

Description

Type of resource text
Form electronic; electronic resource; remote
Extent 1 online resource.
Publication date 2013
Issuance monographic
Language English

Creators/Contributors

Associated with Zhang, Xiaomeng
Associated with Stanford University, Department of Electrical Engineering.
Primary advisor Xing, Lei
Thesis advisor Xing, Lei
Thesis advisor Pauly, John (John M.)
Thesis advisor Ye, Yinyu
Advisor Pauly, John (John M.)
Advisor Ye, Yinyu

Subjects

Genre Theses

Bibliographic information

Statement of responsibility Xiaomeng Zhang.
Note Submitted to the Department of Electrical Engineering.
Thesis Thesis (Ph.D.)--Stanford University, 2013.
Location electronic resource

Access conditions

Copyright
© 2013 by Xiaomeng Zhang
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

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