Synthesis of microfluidic chips

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Abstract/Contents

Abstract
Microfluidic chips are devices that allow one to manipulate nano- and pico-liters of fluids and microscopic objects, such as cells and complex molecules, and are widely employed in bioengineering, molecular biology, chemistry and adjacent fields. We focus our work on soft lithography technology used to create microfluidic chips in a number of bio labs. The growing complexity of these chips increases the probability and the cost of a design mistake, thus making them harder to design and debug. In this thesis, we address these challenges by introducing appropriate design tools. First, we will present a robust compact modelling framework that enables rapid simulations of microfluidic chips via existing circuit simulators, such as SPICE, and validate these models on two simple devices, a long channel and a pump. Then, we frame our model as a geometric program, enabling us to perform fast and global optimizations of complete chip designs. Finally, we introduce a synthesis tool that conceives a design of a chip using parameterized building blocks and optimizes its performance.

Description

Type of resource text
Form electronic; electronic resource; remote
Extent 1 online resource.
Publication date 2013
Issuance monographic
Language English

Creators/Contributors

Associated with Kibardin, Vladimir
Associated with Stanford University, Department of Electrical Engineering.
Primary advisor Horowitz, Mark (Mark Alan)
Thesis advisor Horowitz, Mark (Mark Alan)
Thesis advisor Boyd, Stephen P
Thesis advisor Weaver, James
Advisor Boyd, Stephen P
Advisor Weaver, James

Subjects

Genre Theses

Bibliographic information

Statement of responsibility Vladimir Kibardin.
Note Submitted to the Department of Electrical Engineering.
Thesis Thesis (Ph.D.)--Stanford University, 2013.
Location electronic resource

Access conditions

Copyright
© 2013 by Vladimir Vladimirovich Kibardin

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