Crosslinking strategies for 3D bioprinting of engineered hydrogels
Abstract/Contents
- Abstract
- 3D bioprinting has demonstrated potential for spatially patterning cells and materials together to create structures that recapitulate native tissue. By mimicking these structural features, bioprinted constructs can serve as in vitro models for basic research or can be implanted into the body for regenerative medicine applications. However, this technique is limited by a lack of suitable soft materials for use as bioinks since it remains challenging to design materials that are both printable and can support cell culture. In addition, as matrix material properties are known to influence cell phenotype and behavior, it is becoming increasingly important to tailor the bioink's properties to each individual cell type in order to create more complex, functional printed structures. In this thesis, I explore how engineered, tunable hydrogels can be used to address the current limitations of 3D bioprinting and then develop crosslinking strategies to control the mechanical, biochemical, and dynamic behavior of bioink materials before and after printing.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2022; ©2022 |
| Publication date | 2022; 2022 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Hull, Sarah Mei |
|---|---|
| Degree supervisor | Dunn, Alexander Robert |
| Degree supervisor | Heilshorn, Sarah |
| Thesis advisor | Dunn, Alexander Robert |
| Thesis advisor | Heilshorn, Sarah |
| Thesis advisor | Myung, David |
| Degree committee member | Myung, David |
| Associated with | Stanford University, Department of Chemical Engineering |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Sarah Mei Hull. |
|---|---|
| Note | Submitted to the Department of Chemical Engineering. |
| Thesis | Thesis Ph.D. Stanford University 2022. |
| Location | https://purl.stanford.edu/vq874hx8635 |
Access conditions
- Copyright
- © 2022 by Sarah Mei Hull
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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