Dynamic contrast-enhanced breast MRI
Abstract/Contents
- Abstract
- T1-weighted dynamic contrast-enhanced (DCE) breast MRI has shown high sensitivity in detecting tumors, but has suffered from low specificity. Accuracy of tumor detection and characterization is enhanced by high temporal and spatial resolution, high signal-to-noise ratio (SNR), reliable fat suppression, and reduction of flow artifacts. This thesis presents imaging techniques for improving DCE breast MRI in terms of imaging speed and image quality. It first demonstrates that slab-phase modulation of the two breast slabs improves parallel imaging quality in terms of SNR and aliasing artifacts. Second, it presents temporal acceleration scheme by using parallel imaging to achieve high temporal resolution. Thorough patient study results are also included. Third, it shows that fat suppression can be improved by applying independent shimming to each breast through in vivo experiments. Finally, it demonstrates that partial saturation can eliminate flow artifacts efficiently in RF-spoiled gradient-echo sequences. This technique would be helpful to quantification of kinetic parameters from DCE-MRI.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2010 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Han, Misung |
|---|---|
| Associated with | Stanford University, Department of Electrical Engineering |
| Primary advisor | Hargreaves, Brian Andrew |
| Thesis advisor | Hargreaves, Brian Andrew |
| Thesis advisor | Daniel, Bruce (Bruce Lewis) |
| Thesis advisor | Pauly, John (John M.) |
| Advisor | Daniel, Bruce (Bruce Lewis) |
| Advisor | Pauly, John (John M.) |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Misung Han. |
|---|---|
| Note | Submitted to the Department of Electrical Engineering. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2010. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2010 by Misung Han
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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