Bioengineered 3D cancer model to decipher brain tumor-niche interactions
Abstract/Contents
- Abstract
- Brain tumors remain as one of the most challenging tumors to treat. A critical barrier to progress in improving clinical outcomes is the lack of faithful experimental models for deciphering brain tumor biology and screening novel drug candidates. By integrating principles from cancer biology, materials science, and tissue engineering, we have developed novel 3D in vitro cancer models using biomimetic hydrogels that may bridge the gap between conventional 2D culture and animal models. Such bioengineered 3D cancer models would enable mechanistic studies to test novel hypotheses for tumor progression and accelerate the discovery of new therapeutics.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2016 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Wang, Christine |
|---|---|
| Associated with | Stanford University, Department of Bioengineering. |
| Primary advisor | Yang, Fan, (Bioengineering researcher and teacher) |
| Thesis advisor | Yang, Fan, (Bioengineering researcher and teacher) |
| Thesis advisor | Grant, Gerald |
| Thesis advisor | Monje-Deisseroth, Michelle |
| Advisor | Grant, Gerald |
| Advisor | Monje-Deisseroth, Michelle |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Christine Wang. |
|---|---|
| Note | Submitted to the Department of Bioengineering. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2016. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2016 by Christine Wang
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
Also listed in
Loading usage metrics...