Tools for coronary MR angiography : non-cartesian trajectories and motion-corrected reconstructions

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Abstract/Contents

Abstract
X-ray coronary angiography remains the predominant technique for coronary artery examination, yet it exposes both patients and operators to ionizing radiation and is invasive. Despite strong demand for non-invasive and safer alternatives, the clinical adoption of coronary MR angiography has been slow. The primary challenges in coronary MR angiography are its prolonged scan time and limited resolution. Because coronary arteries often follow tortuous paths and have relatively small diameters, high resolving power is required. Additionally, whole-heart imaging is preferred over target-volume methods, as it reduces operator dependency. Achieving large volumetric coverage at high resolution demands collecting a significant amount of data. However, continuous myocardial movement restricts data collection to specific cardiac cycles, necessitating the segmented data acquisition over multiple heartbeats. Consequently, coronary MR angiography is slow and susceptible to both respiratory and cardiac motion. This dissertation introduces several tools for coronary MR angiography categorized into non-Cartesian trajectory design and non-rigid motion-corrected reconstruction. Non-Cartesian trajectories often exhibit higher sampling efficiency and greater robustness against undersampling compared to traditional rectilinear approaches, making them particularly useful for reducing the overall scan duration. Because non-rigid models capture a wide range of transformations, non-rigid motion-corrected reconstruction reduces resolution loss due to respiratory and cardiac motion.

Description

Type of resource text
Form electronic resource; remote; computer; online resource
Extent 1 online resource.
Place California
Place [Stanford, California]
Publisher [Stanford University]
Copyright date 2024; ©2024
Publication date 2024; 2024
Issuance monographic
Language English

Creators/Contributors

Author Jang, Kwang Eun
Degree supervisor Nishimura, Dwight George
Thesis advisor Nishimura, Dwight George
Thesis advisor Coleman, Todd, (Of University of California, San Diego)
Thesis advisor Vasanawala, Shreyas
Degree committee member Coleman, Todd, (Of University of California, San Diego)
Degree committee member Vasanawala, Shreyas
Associated with Stanford University, School of Engineering
Associated with Stanford University, Department of Bioengineering

Subjects

Genre Theses
Genre Text

Bibliographic information

Statement of responsibility Kwang Eun Jang.
Note Submitted to the Department of Bioengineering.
Thesis Thesis Ph.D. Stanford University 2024.
Location https://purl.stanford.edu/sc219dv4593

Access conditions

Copyright
© 2024 by Kwangeun Jang
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

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