Advances in breast MRI

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Abstract/Contents

Abstract
Breast magnetic resonance imaging (MRI) is becoming an increasingly valuable technology for breast cancer detection, especially for women at high risk for the disease. Stanford Hospital alone performed approximately 1,000 breast MRIs last year. This demand and need to increase specificity of breast MRI motivates improving current breast MR protocols, as well as exploring new applications of MR technology to breast imaging. Most clinical breast MR exams are performed at a 1.5T field strength. 3T scanners, however, are becoming more prevalent in the clinical setting and thus the breast MR protocol needs to be tuned accordingly. The first project includes measurements of T1 and T2 of breast fat and glandular tissue at 1.5T and 3T and the corresponding recommendation for altering the TR and TE for 3T breast imaging. The beating heart posterior to the breast often produces artifacts in breast MR images. The second project is a cylindrical saturation method that reduces unwanted signal from the heart while avoiding signal loss from the breast tissue of interest. Detecting tumor oxygenation non-invasively may give insight on tumor differentiation, predict susceptibility to antiangiogenic therapeutics, and monitor chemotherapeutics. The third project introduces the application of BOLD contrast imaging, a technique usually applied in functional brain MR imaging for characterizing tumor oxygenation in the breast.

Description

Type of resource text
Form electronic; electronic resource; remote
Extent 1 online resource.
Publication date 2010
Issuance monographic
Language English

Creators/Contributors

Associated with Rakow-Penner, Rebecca
Associated with Stanford University, Department of Biophysics.
Primary advisor Glover, Gary H
Thesis advisor Glover, Gary H
Thesis advisor Daniel, Bruce (Bruce Lewis)
Thesis advisor Hargreaves, Brian Andrew
Advisor Daniel, Bruce (Bruce Lewis)
Advisor Hargreaves, Brian Andrew

Subjects

Genre Theses

Bibliographic information

Statement of responsibility Rebecca Rakow-Penner.
Note Submitted to the Department of Biophysics.
Thesis Ph.D. Stanford University 2010
Location electronic resource

Access conditions

Copyright
© 2010 by Rebecca Rakow-Penner
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

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