Advances in breast MRI
Abstract/Contents
- Abstract
- Breast magnetic resonance imaging (MRI) is becoming an increasingly valuable technology for breast cancer detection, especially for women at high risk for the disease. Stanford Hospital alone performed approximately 1,000 breast MRIs last year. This demand and need to increase specificity of breast MRI motivates improving current breast MR protocols, as well as exploring new applications of MR technology to breast imaging. Most clinical breast MR exams are performed at a 1.5T field strength. 3T scanners, however, are becoming more prevalent in the clinical setting and thus the breast MR protocol needs to be tuned accordingly. The first project includes measurements of T1 and T2 of breast fat and glandular tissue at 1.5T and 3T and the corresponding recommendation for altering the TR and TE for 3T breast imaging. The beating heart posterior to the breast often produces artifacts in breast MR images. The second project is a cylindrical saturation method that reduces unwanted signal from the heart while avoiding signal loss from the breast tissue of interest. Detecting tumor oxygenation non-invasively may give insight on tumor differentiation, predict susceptibility to antiangiogenic therapeutics, and monitor chemotherapeutics. The third project introduces the application of BOLD contrast imaging, a technique usually applied in functional brain MR imaging for characterizing tumor oxygenation in the breast.
Description
Type of resource | text |
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Form | electronic; electronic resource; remote |
Extent | 1 online resource. |
Publication date | 2010 |
Issuance | monographic |
Language | English |
Creators/Contributors
Associated with | Rakow-Penner, Rebecca |
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Associated with | Stanford University, Department of Biophysics. |
Primary advisor | Glover, Gary H |
Thesis advisor | Glover, Gary H |
Thesis advisor | Daniel, Bruce (Bruce Lewis) |
Thesis advisor | Hargreaves, Brian Andrew |
Advisor | Daniel, Bruce (Bruce Lewis) |
Advisor | Hargreaves, Brian Andrew |
Subjects
Genre | Theses |
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Bibliographic information
Statement of responsibility | Rebecca Rakow-Penner. |
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Note | Submitted to the Department of Biophysics. |
Thesis | Ph.D. Stanford University 2010 |
Location | electronic resource |
Access conditions
- Copyright
- © 2010 by Rebecca Rakow-Penner
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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