Internal Beam Annihilation Therapy: A Novel Approach to Radiation Therapy

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Abstract/Contents

Abstract: Photon external beam therapy is currently the most widely used modality of radiotherapy in the treatment of cancer. However, due to the exponential characteristics of photon attenuation in matter, most of the energy is deposited before the beam even reaches the tumor inside the body. This results in poor dose conformity and large entrance doses, causing undesired irradiation of healthy tissue which can ultimately lead to toxicity and secondary cancers. In this study we describe a new theoretical modality of radiotherapy termed Internal Beam Annihilation Therapy (IBAT) which in an ideal model case can exhibit far superior dose contrast and conformity by using muon anti-muon annihilation at the tumor site. Using Monte Carlo simulation in conjunction with FLUKA, a particle transport code, we evaluate the energy deposition distribution of such a modality and compare its unique characteristics with those of existing modalities.

Type of resource	text
Date created	2011

Author	Liu, Michael
Department	Stanford University, Department of Physics
Primary advisor	Colby, Eric
Advisor	Burchat, Patricia

Subject	cancer treatment
Subject	radiotherapy
Subject	Internal Beam Annihilation Therapy
Subject	IBAT
Genre	Thesis

Location	https://purl.stanford.edu/rt187sc7864

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License: This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

Preferred Citation: Liu, Michael (2011). Internal beam annihilation therapy: A novel approach to radiation therapy. Stanford Digital Repository. Available at http://purl.stanford.edu/rt187sc7864.

Undergraduate Theses, Department of Physics

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