Electronic readout strategies for silicon photomultiplier-based positron emission tomography detectors
Abstract/Contents
- Abstract
- The new generation of positron emission tomography (PET) scanners based on silicon photo-multiplier (SiPM) technology require thousands of readout channels. Due to the complexity of such systems, potential advances in PET such as 3D position sensitive detectors, depth of interaction (DOI) and optimized time of flight (TOF) design have not been fully implemented in commercial scanners. This thesis proposes and tests readout strategies that greatly simplify the readout of advanced PET detectors. A pulse width modulation (PWM) readout strategy that allows for multiplexing without signal degradation is demonstrated on an ultra-high resolution 3D position- ing PET detector. The readout successfully resolves 0.5 mm x 0.5 mm x 1.0 mm LYSO crystals. The effects of multiplexing readout channels of state-of-the-art SiPM arrays on timing resolution are also thoroughly investigated. A TOF DOI detector with sub 300 ps full width half maximum (FWHM) coincidence time resolution is demonstrated with a 32:1 crystal to timing channel multiplexing ratio, and a passive binary positioning scheme. This module is then tested using analog and digital electro-optical readout to enable MR compatibility for a simultaneous PET/MR design. Finally, 3D printed phantoms to test the effects of these novel PET detectors on image quality are introduced. The strategies presented in this thesis significantly simplify PET readout, while increasing its imaging capabilities.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2016 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Bieniosek, Matthew |
|---|---|
| Associated with | Stanford University, Department of Electrical Engineering. |
| Primary advisor | Levin, Craig |
| Thesis advisor | Levin, Craig |
| Thesis advisor | Khuri-Yakub, Butrus T, 1948- |
| Thesis advisor | Murmann, Boris |
| Advisor | Khuri-Yakub, Butrus T, 1948- |
| Advisor | Murmann, Boris |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Matthew Bieniosek. |
|---|---|
| Note | Submitted to the Department of Electrical Engineering. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2016. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2016 by Matthew Francis Bieniosek
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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