Axi-cel CAR T single-cell data
Abstract/Contents
- Abstract
- This repository contains metadata and single-cell data used to generate figures in the manuscript entitled: "Post-infusion Treg-like CAR T cells identify patients resistant to CD19-CAR therapy". Included here: CSV files containing patient cohort metadata, summary statistics and quantitative PCR results; FCS files for flow and mass cytometry data; processed Seurat object for single-cell sequencing data. Raw single-cell sequencing data, cellranger alignment results, and metadata are available through the Gene Expression Omnibus (https://www.ncbi.nlm.nih.gov/geo; GEO accession number: GSE168940). With questions, please reach out to Zinaida Good (zinaida@stanford.edu) or Crystal L. Mackall (cmackall@stanford.edu).
Description
| Type of resource | Dataset |
|---|---|
| Date created | 2018 - 2022 |
| Date modified | July 2, 2022; October 21, 2022 |
| Publication date | July 1, 2022 |
Creators/Contributors
| Author | Good, Zinaida | |
|---|---|---|
| Author | Spiegel, Jay | |
| Contributor | Sahaf, Bita | |
| Contributor | Malipatlolla, Meena | |
| Contributor | Ehlinger, Zach | |
| Contributor | Kurra, Sreevidya | |
| Contributor | Desai, Moksha | |
| Contributor | Reynolds, Warren | |
| Contributor | Wong Lin, Anita | |
| Contributor | Vandris, Panayiotis | |
| Contributor | Wu, Fang | |
| Contributor | Prabhu, Snehit | |
| Contributor | Hamilton, Mark | |
| Contributor | Tamaresis, John | |
| Contributor | Hanson, Paul | |
| Contributor | Patel, Shabnum | |
| Contributor | Feldman, Steven | |
| Contributor | Frank, Matthew | |
| Contributor | Baird, John | |
| Contributor | Muffly, Lori | |
| Contributor | Claire, Gursharan | |
| Contributor | Craig, Juliana | |
| Contributor | Kong, Katherine | |
| Contributor | Wagh, Dhananjay | |
| Contributor | Coller, John | |
| Contributor | Bendall, Sean | |
| Contributor | Tibshirani, Robert | |
| Contributor | Plevritis, Sylvia | |
| Research team head | Miklos, David | |
| Research team head | Mackall, Crystal |
Subjects
| Subject | CAR T cell |
|---|---|
| Subject | axicabtagene ciloleucel |
| Subject | lymphoma |
| Subject | CD57 |
| Subject | Helios |
| Subject | T-bet |
| Subject | mass cytometry |
| Subject | CyTOF |
| Subject | scRNA-seq |
| Subject | CITE-seq |
| Genre | Data |
| Genre | Data sets |
| Genre | Dataset |
Bibliographic information
| Related item |
|
|---|---|
| DOI | https://doi.org/10.25740/qb215vz6111 |
| Location | https://purl.stanford.edu/qb215vz6111 |
Access conditions
- Use and reproduction
- User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
- License
- This work is licensed under an Open Data Commons Public Domain Dedication & License 1.0.
Preferred citation
- Preferred citation
- Good, Z., Spiegel, J., Sahaf, B., Malipatlolla, M., Ehlinger, Z., Kurra, S., Desai, M., Reynolds, W., Wong Lin, A., Vandris, P., Wu, F., Prabhu, S., Hamilton, M., Tamaresis, J., Hanson, P., Patel, S., Feldman, S., Frank, M., Baird, J., Muffly, L., Claire, G., Craig, J., Kong, K., Wagh, D., Coller, J., Bendall, S., Tibshirani, R., Plevritis, S., Miklos, D., and Mackall, C. (2022). Axi-cel CAR T single-cell data. Stanford Digital Repository. Available at https://purl.stanford.edu/qb215vz6111
Collection
Stanford Research Data
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