Axi-cel CAR T single-cell data

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Abstract/Contents

Abstract
This repository contains metadata and single-cell data used to generate figures in the manuscript entitled: "Post-infusion Treg-like CAR T cells identify patients resistant to CD19-CAR therapy". Included here: CSV files containing patient cohort metadata, summary statistics and quantitative PCR results; FCS files for flow and mass cytometry data; processed Seurat object for single-cell sequencing data. Raw single-cell sequencing data, cellranger alignment results, and metadata are available through the Gene Expression Omnibus (https://www.ncbi.nlm.nih.gov/geo; GEO accession number: GSE168940). With questions, please reach out to Zinaida Good (zinaida@stanford.edu) or Crystal L. Mackall (cmackall@stanford.edu).

Description

Type of resource Dataset
Date created 2018 - 2022
Date modified July 2, 2022; October 21, 2022
Publication date July 1, 2022

Creators/Contributors

Author Good, Zinaida
Author Spiegel, Jay
Contributor Sahaf, Bita
Contributor Malipatlolla, Meena
Contributor Ehlinger, Zach
Contributor Kurra, Sreevidya
Contributor Desai, Moksha
Contributor Reynolds, Warren
Contributor Wong Lin, Anita
Contributor Vandris, Panayiotis
Contributor Wu, Fang
Contributor Prabhu, Snehit
Contributor Hamilton, Mark
Contributor Tamaresis, John
Contributor Hanson, Paul
Contributor Patel, Shabnum
Contributor Feldman, Steven
Contributor Frank, Matthew
Contributor Baird, John
Contributor Muffly, Lori
Contributor Claire, Gursharan
Contributor Craig, Juliana
Contributor Kong, Katherine
Contributor Wagh, Dhananjay
Contributor Coller, John
Contributor Bendall, Sean
Contributor Tibshirani, Robert
Contributor Plevritis, Sylvia
Research team head Miklos, David
Research team head Mackall, Crystal

Subjects

Subject CAR T cell
Subject axicabtagene ciloleucel
Subject lymphoma
Subject CD57
Subject Helios
Subject T-bet
Subject mass cytometry
Subject CyTOF
Subject scRNA-seq
Subject CITE-seq
Genre Data
Genre Data sets
Genre Dataset

Bibliographic information

Related item
DOI https://doi.org/10.25740/qb215vz6111
Location https://purl.stanford.edu/qb215vz6111

Access conditions

Use and reproduction
User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
License
This work is licensed under an Open Data Commons Public Domain Dedication & License 1.0.

Preferred citation

Preferred citation
Good, Z., Spiegel, J., Sahaf, B., Malipatlolla, M., Ehlinger, Z., Kurra, S., Desai, M., Reynolds, W., Wong Lin, A., Vandris, P., Wu, F., Prabhu, S., Hamilton, M., Tamaresis, J., Hanson, P., Patel, S., Feldman, S., Frank, M., Baird, J., Muffly, L., Claire, G., Craig, J., Kong, K., Wagh, D., Coller, J., Bendall, S., Tibshirani, R., Plevritis, S., Miklos, D., and Mackall, C. (2022). Axi-cel CAR T single-cell data. Stanford Digital Repository. Available at https://purl.stanford.edu/qb215vz6111

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