Methods for monitoring lesion formation during thermal therapies using magnetic resonance imaging
Abstract/Contents
- Abstract
- The first part of this thesis will rely on previously established lesion evaluation modalities such as diffusion to monitor lesion formation. A method to simultaneously monitor temperature and diffusion will be proposed and implemented to remove temperature dependent changes from diffusion measurements in order to highlight the diffusion changes associated with loss of tissue viability. The evolution of how tissue responds to treatment will be analyzed using this new insight on lesion development. The second part of this thesis will introduce a novel contrast mechanism to monitor thermal treatments. This contrast is based on a steady-state sequence called Double Echo in Steady State (DESS); the second echo in DESS is designed to be sensitive to diffusion. A strategy to incorporate this sequence to treatment monitoring will be proposed and implemented through simulations and validated with phantom experiments. Preliminary experiments using this contrast mechanism to monitor and evaluate lesions in vivo will also be presented.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2016 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Plata-Camargo, Juan Camilo |
|---|---|
| Associated with | Stanford University, Department of Bioengineering. |
| Primary advisor | Pauly, Kim Butts (Kim Rosemary Butts) |
| Thesis advisor | Pauly, Kim Butts (Kim Rosemary Butts) |
| Thesis advisor | Ghanouni, Pejman |
| Thesis advisor | Pelc, Norbert J |
| Advisor | Ghanouni, Pejman |
| Advisor | Pelc, Norbert J |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Juan Camilo Plata-Camargo. |
|---|---|
| Note | Submitted to the Department of Bioengineering. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2016. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2016 by Juan Camilo Plata-Camargo
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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