The dynamic linkage of actin to focal adhesions
Abstract/Contents
- Abstract
- Cells exert cytoskeletally-generated force to the surrounding extracellular matrix using specialized integrin-based focal adhesion complexes. Part 1 characterizes force transduction of fibroblasts in a soft fibrin extracellular matrix. Part 2 characterizes the force-dependent kinetics of the bond between focal adhesion protein talin and F-actin using single-molecule force spectroscopy.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2020; ©2020 |
| Publication date | 2020; 2020 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Owen, Leanna Marie |
|---|---|
| Degree supervisor | Dunn, Alexander Robert |
| Thesis advisor | Dunn, Alexander Robert |
| Thesis advisor | Weis, William I |
| Thesis advisor | Zuchero, J |
| Degree committee member | Weis, William I |
| Degree committee member | Zuchero, J |
| Associated with | Stanford University, Biophysics Program |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Leanna Owen. |
|---|---|
| Note | Submitted to the Biophysics Program. |
| Thesis | Thesis Ph.D. Stanford University 2020. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2020 by Leanna Marie Owen
- License
- This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).
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