Identifying and understanding microtubule associated proteins
Abstract/Contents
- Abstract
- Microtubules are intracellular polymers that are necessary for various essential processes ranging from cell division to maintaining cell structure. However, microtubules must adopt specific patterns in many of these processes even though the polymers are built using the same subunit. To achieve this range of patterns, microtubule associated proteins (MAPs) modulate microtubules by performing functions like nucleation and crosslinking. While the localization and function of many MAPs are known, we still do not understand how most microtubule patterns are achieved nor the role of MAPs in this patterning. In this study we used C. elegans as a model to find that the understudied MAP9 has a conserved and specific localization to microtubule doublets.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2023; ©2023 |
| Publication date | 2023; 2023 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Tran, Michael Viet |
|---|---|
| Degree supervisor | Feldman, Jessica L |
| Thesis advisor | Feldman, Jessica L |
| Thesis advisor | Shen, Kang, 1972- |
| Thesis advisor | Stearns, Tim |
| Degree committee member | Shen, Kang, 1972- |
| Degree committee member | Stearns, Tim |
| Associated with | Stanford University, School of Humanities and Sciences |
| Associated with | Stanford University, Department of Biology |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Michael V. Tran. |
|---|---|
| Note | Submitted to the Department of Biology. |
| Thesis | Thesis Ph.D. Stanford University 2023. |
| Location | https://purl.stanford.edu/ns349yy4873 |
Access conditions
- Copyright
- © 2023 by Michael Viet Tran
- License
- This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).
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