Genomic methods and studies in epidermal differentiation
Abstract/Contents
- Abstract
- Multicellular organisms are composed of diverse, functionally specialized cell types. However each cell contains essentially the same DNA sequence, the genetic information which encodes instructions for constructing the cellular machinery and guiding cellular behavior. How do cells achieve such diverse functions and behaviors from the same genetic endowment? A key part of the answer lies in selective usage of the genetic material (the genome) -- while one cell may act on a subset of the genome, a neighboring cell may act on a largely distinct subset of the genome in order to achieve distinct functions. This thesis describes insights into the molecular machinery that cells employ to achieve selective usage of the genome as well as novel methods to interrogate this machinery.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2018; ©2018 |
| Publication date | 2018; 2018 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Rubin, Adam |
|---|---|
| Degree supervisor | Khavari, Paul A |
| Thesis advisor | Khavari, Paul A |
| Thesis advisor | Diehn, Maximilian |
| Thesis advisor | Majeti, Ravindra, 1972- |
| Degree committee member | Diehn, Maximilian |
| Degree committee member | Majeti, Ravindra, 1972- |
| Associated with | Stanford University, Stem Cell Biology and Regenerative Medicine Program. |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Adam Rubin. |
|---|---|
| Note | Submitted to the Stem Cell Biology and Regenerative Medicine Program. |
| Thesis | Thesis Ph.D. Stanford University 2018. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2018 by Adam Joseph Rubin
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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