Quantitative magnetic characterization of single cells
Abstract/Contents
- Abstract
- Iron oxide based magnetic nanoparticles are used in a variety of biomedical applications, such as targeted drug delivery, cancer therapy and MRI. As many of these applications approach the single cell level, it becomes necessary to develop magnetic characterization techniques with improved sensitivity and spatial resolution. In this thesis, I present magnetic measurements of individual magnetotactic bacteria and iron loaded cancer cells, made with scanning SQUID microscopy. I also describe the modeling technique we use to calculate the dipole moments of these individual cells from their corresponding scanning SQUID magnetometry images. By measuring many individual cells, we can compare our results with bulk magnetometry measurements to gain additional insights. Such single cell magnetic measurements will be helpful for optimizing image contrast in single cell MR tracking and other single cell applications.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2013 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Qian, Lisa |
|---|---|
| Associated with | Stanford University, Department of Applied Physics. |
| Primary advisor | Moler, Kathryn A |
| Thesis advisor | Moler, Kathryn A |
| Thesis advisor | Beasley, Malcolm |
| Thesis advisor | Fisher, Ian R. (Ian Randal) |
| Advisor | Beasley, Malcolm |
| Advisor | Fisher, Ian R. (Ian Randal) |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Lisa Qian. |
|---|---|
| Note | Submitted to the Department of Applied Physics. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2013. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2013 by Lisa Chenyu Qian
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