Polygenic Influence on Educational Attainment
Abstract/Contents
- Abstract
- Recent studies have begun to uncover the genetic architecture of educational attainment. We build on this work using genome-wide data from siblings in the National Longitudinal Study of Adolescent to Adult Health (Add Health). We measure the genetic predisposition of siblings to educational attainment using polygenic scores. We then test how polygenic scores are related to social environments and educational outcomes. In Add Health, genetic predisposition to educational attainment is patterned across the social environment. Participants with higher polygenic scores were more likely to grow up in socially advantaged families. Even so, the previously published genetic associations appear to be causal. Among pairs of siblings, the sibling with the higher polygenic score typically went on to complete more years of schooling as compared to their lower-scored co-sibling. We found subtle differences between sibling fixed-effect estimates of the genetic effect versus those based on unrelated individuals.
Description
Type of resource | text |
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Date created | 2015 |
Creators/Contributors
Author | Domingue, Benjamin W. | |
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Author | Belsky, Daniel W. | |
Author | Conley, Dalton | |
Author | Harris, Kathleen Mullan | |
Author | Boardman, Jason D. |
Subjects
Subject | polygenic score |
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Subject | educational attainment |
Subject | Add Health |
Subject | genetic risk score |
Genre | Article |
Bibliographic information
Related item |
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Location | https://purl.stanford.edu/nj930dt8973 |
Access conditions
- Use and reproduction
- User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
- License
- This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).
Preferred citation
- Preferred Citation
- Domingue, B., Belsky, D.W., Conley D., Harris K.M., and Boardman, J.D. (2015) Polygenic influence of educational attainment. AERA OPEN, DOI: 10.1177/2332858415599972.
Collection
Graduate School of Education Open Archive
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- Contact
- ben.domingue@stanford.edu
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