Thermal perturbation as a contrast mechanism in bioimpedance spectroscopy
Abstract/Contents
- Abstract
- There is considerable interest in quantifying the health of individuals in greater detail and at finer time scales. One aspect of this has been the use of wearable sensors. However, there exist very few sensing techniques that can yield meaningful health information without breaking the skin, an important factor for comfort, safety, and widespread adoption. This thesis presents an entirely new way to measure the electrical impedance spectrum of blood noninvasively. The impedance spectrum of blood in the medium and high frequency RF bands (300 kHz to 30 MHz) has long been known to encode information about red blood cell state and interaction, due to its sensitivity to cell shape and aggregation. In practice, however, simple approaches to noninvasive measurement face challenges due to the confounding effect of surrounding tissue. The technique presented in this thesis makes use of the heat transport by the bulk motion of blood in the superficial vasculature as a contrast mechanism. Measurements on a vascular tissue phantom demonstrate that the technique can recover the impedance spectrum noninvasively, though practical concerns likely limit viability in a clinical context.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2019; ©2019 |
| Publication date | 2019; 2019 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Heywood, Daniel |
|---|---|
| Degree supervisor | Kenny, Thomas William |
| Thesis advisor | Kenny, Thomas William |
| Thesis advisor | Arbabian, Amin |
| Thesis advisor | Soh, H. Tom |
| Degree committee member | Arbabian, Amin |
| Degree committee member | Soh, H. Tom |
| Associated with | Stanford University, Department of Mechanical Engineering. |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Daniel Heywood. |
|---|---|
| Note | Submitted to the Department of Mechanical Engineering. |
| Thesis | Thesis Ph.D. Stanford University 2019. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2019 by Daniel Heywood
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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