Hunting down host targets for host-directed therapies through forward genetic screens
Abstract/Contents
- Abstract
- Infectious diseases have plagued humans for centuries, and with the rise in antimicrobial resistance, there is a pressing need to develop novel strategies for combating pathogens. Host-directed therapies offer a promising alternative to traditional antimicrobials that directly target the pathogen. Furthermore, the identification of targets for the development of host-directed therapies has been accelerated by the advent of next-generation screening technology. This thesis presents examples of applying forward genetic screens to the identification of novel and attractive host targets for the development of host-directed therapies.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2018; ©2018 |
| Publication date | 2018; 2018 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Diep, Jonathan |
|---|---|
| Degree supervisor | Carette, Jan, 1971- |
| Thesis advisor | Carette, Jan, 1971- |
| Thesis advisor | Kim, Peter, 1958- |
| Thesis advisor | Kirkegaard, Karla |
| Thesis advisor | Yeh, Ellen |
| Degree committee member | Kim, Peter, 1958- |
| Degree committee member | Kirkegaard, Karla |
| Degree committee member | Yeh, Ellen |
| Associated with | Stanford University, Department of Microbiology and Immunology. |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Jonathan Diep. |
|---|---|
| Note | Submitted to the Department of Microbiology and Immunology. |
| Thesis | Thesis Ph.D. Stanford University 2018. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2018 by Jonathan Diep
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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