The effects of relatedness and population structure on patterns of genomic sharing

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Abstract/Contents

Abstract
In this dissertation, I use several approaches to study patterns of genomic sharing. Chapters 2 and 3 take a theoretical approach, modeling the effect of consanguinity on patterns of genomic sharing. In Chapter 4, I describe a new method to detect IBD segments between closely related individuals. Lastly, in Chapter 5, I take a data-driven approach, analyzing levels of genomic segment sharing as well as genotype sharing to understand the genetic relationship between ancient and modern Indigenous individuals in North America.

Description

Type of resource text
Form electronic resource; remote; computer; online resource
Extent 1 online resource.
Place California
Place [Stanford, California]
Publisher [Stanford University]
Copyright date 2021; ©2021
Publication date 2021; 2021
Issuance monographic
Language English

Creators/Contributors

Author Severson, Alissa Lehr
Degree supervisor Rosenberg, Noah
Thesis advisor Rosenberg, Noah
Thesis advisor Montgomery, Stephen, 1979-
Thesis advisor Pritchard, Jonathan D
Thesis advisor Tang, Hua
Degree committee member Montgomery, Stephen, 1979-
Degree committee member Pritchard, Jonathan D
Degree committee member Tang, Hua
Associated with Stanford University, Department of Genetics

Subjects

Genre Theses
Genre Text

Bibliographic information

Statement of responsibility Alissa Lehr Severson.
Note Submitted to the Department of Genetics.
Thesis Thesis Ph.D. Stanford University 2021.
Location https://purl.stanford.edu/mn208ct3165

Access conditions

Copyright
© 2021 by Alissa Lehr Severson
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

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