A role for a mechanosensitive ion channel in long-distance electrical signaling in Arabidopsis
Abstract/Contents
- Abstract
- Plants contend with a myriad of environmental stressors, including insect herbivory. To defend against insect herbivory, plants employ defense responses to mitigate damage. Insects are mobile organisms, therefore, wounded tissues in plants send systemic signals to engage defense mechanisms in unwounded tissues to attenuate further herbivory. These defense signals are mechanistically complex. Long-distance electrical signals are speculated to convey the wound signal to distal tissues. Ionotropic glutamate receptors have previously been identified as key components of the electrical defense signal, but additional molecular components are expected to play a role as well. To uncover new molecular players, I performed a genetic screen which revealed that the mechanosensitive ion channel, MSL10, is important for wound induced long distance signaling. In Chapter 1, I review wound signaling in plants and explore the various mechanisms proposed to drive long-distance signals. Chapter 2 describes the discovery of the MSL10 phenotype and characterization of its role in electrical wound signaling. In Chapter 3, I explore the cell biology of MSL10 and how localization in the vasculature is important for signaling. I employed genetically encoded biosensors to study signaling events in plants to better understand their spatial patterning in Chapter 4. Finally, Chapter 5 summarizes the key findings of the thesis project and proposes new avenues of research to answer new open questions. Taken together, this work within the thesis provides a new foundation of knowledge for long-distance plant signaling and opens exciting new areas of study.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2021; ©2021 |
| Publication date | 2021; 2021 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Moe-Lange, Jacob |
|---|---|
| Degree supervisor | Frommer, Wolf B, 1958- |
| Degree supervisor | Mudgett, Mary Beth, 1967- |
| Thesis advisor | Frommer, Wolf B, 1958- |
| Thesis advisor | Mudgett, Mary Beth, 1967- |
| Thesis advisor | Ehrhardt, David (David Walter) |
| Thesis advisor | Lin, Michael Z |
| Thesis advisor | Shen, Kang, 1972- |
| Degree committee member | Ehrhardt, David (David Walter) |
| Degree committee member | Lin, Michael Z |
| Degree committee member | Shen, Kang, 1972- |
| Associated with | Stanford University, Department of Biology |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Jacob Moe-Lange. |
|---|---|
| Note | Submitted to the Department of Biology. |
| Thesis | Thesis Ph.D. Stanford University 2021. |
| Location | https://purl.stanford.edu/jt588nb0353 |
Access conditions
- Copyright
- © 2021 by Jacob Moe-Lange
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