Bacteriophage as diagnostic and pathogenic factors in human disease
Abstract/Contents
- Abstract
- The human microbiome plays an important role in human health and disease. Study of the human microbiome typically focuses on bacteria, fungi, and viruses which infect mammalian cells. An often-ignored facet of these communities are bacteriophage. These are viruses which infect bacteria with a specificity to the species or strain level. Though bacteriophage do not infect mammalian tissues, they are important in human health and disease. In this dissertation, I will describe our work in exploring the role of bacteriophage in the human body -- from their utility as diagnostic targets in bacterial infections, to their direct and indirect influence on mammalian cells and health outcomes. Collectively, these studies demonstrate that bacteriophage are a critical facet of the human microbiome, in particular in contexts of bacterial infection, and provide new avenues for both diagnostic and prognostic targets in human health and disease.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2023; ©2023 |
| Publication date | 2023; 2023 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Haddock, Naomi Lynn |
|---|---|
| Degree supervisor | Bollyky, Paul |
| Thesis advisor | Bollyky, Paul |
| Thesis advisor | Bhatt, Ami |
| Thesis advisor | Milla, Carlos |
| Thesis advisor | Nicolls, Mark |
| Degree committee member | Bhatt, Ami |
| Degree committee member | Milla, Carlos |
| Degree committee member | Nicolls, Mark |
| Associated with | Stanford University, School of Medicine |
| Associated with | Stanford University, Department of Microbiology and Immunology |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Naomi Lynn Haddock. |
|---|---|
| Note | Submitted to the Department of Microbiology and Immunology. |
| Thesis | Thesis Ph.D. Stanford University 2023. |
| Location | https://purl.stanford.edu/jr006pr7631 |
Access conditions
- Copyright
- © 2023 by Naomi Lynn Haddock
- License
- This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).
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