Dynamic per slice Shimming for Simultaneous Brain and Spinal Cord fMRI
Abstract/Contents
- Abstract
Simultaneous brain and spinal cord functional MRI is emerging as a new tool in study of the central nervous system, but is challenging. Poor B0 homogeneity and small size of spinal cord are principal obstacles to this nascent technology. We extend a dynamic shimming approach, first posed by Finsterbusch for brain/spinal cord, by shimming per slice.
We shim dynamically by optimization of linear gradients and frequency offset for each and every slice in order to minimize off-resonance for both brain and spinal cord. Simultaneous acquisition of brain and spinal cord fMRI is achieved with high spatial resolution in spine by means of echo-planar RF pulse for reduced FOV. Brain slice acquisition is full FOV.
T2*-weighted images of brain and spinal cord are acquired with high clarity and minimal observable image artifacts. fMRI experiments reveal task consistent activation in motor cortices, cerebellum, and C6-T1 spinal segments.
Consistent activation in both brain and spinal cord is observed at individual levels, not only group level. High quality functional results are obtained for a motor task. Because reduced FOV excitation is applicable to any spinal cord section, future continuation of these methods holds great portent.
Description
Type of resource | text |
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Date created | January 2018 |
Date modified | February 22, 2023 |
Publication date | January 23, 2018 |
Creators/Contributors
Author | Islam, Haisam |
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Author | Law, Christine S. W. |
Author | Weber, Kenneth A. |
Author | Mackey, Sean C. |
Author | Glover, Gary H. |
Subjects
Subject | fMRI |
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Subject | simultaneous brain and spinal cord fMRI |
Subject | spinal cord |
Subject | dynamic shimming |
Subject | reduced FOV |
Genre | Text |
Genre | Article |
Bibliographic information
Related item |
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Location | https://purl.stanford.edu/hp797pz5249 |
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- Use and reproduction
- User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
- License
- This work is licensed under a Creative Commons Attribution Non Commercial No Derivatives 4.0 International license (CC BY-NC-ND).
Preferred citation
- Preferred citation
- Islam & Law 2018
Collection
Stanford University Open Access Articles
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- Contact
- cslaw@stanford.edu
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