Development of the capsule ultrasound (CUS) device
Abstract/Contents
- Abstract
- Currently, there is a lack of medical imaging tools required to investigate the multiple layers of the entire small intestine in the gastrointestinal (GI) tract. Some of the existing imaging modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI), used for examining the GI tract, expose the patient to radiation and/or are expensive. To make GI tract assessment easier, doctors use endoscopic ultrasound (EUS) and capsule endoscopy (CE). While EUS provides adequate penetration depth, it is unable to look at the entire small bowel. On the other hand, while CE is able to survey the entire small bowel, it only observes at the superficial layer due to its use of optics. To increase the prevalence of GI tract screening, with particular emphasis on small bowel, we propose to develop the capsule ultrasound (CUS) device, a diagnostic capsule with ultrasound imaging capability. Our envisioned device will measure 2.5 cm in height and 1 cm in diameter. Upon being swallowed by the patient, the CUS device will collect images of the GI tract with 360 degrees field-of-view (FOV) and wirelessly transmit the images to an external recorder for image reconstruction and display. To accomplish this goal, the CUS device will be equipped with a cylindrical transducer array around its perimeter and the associated imaging electronics, for regulating the image acquisition process, as well as a wireless transmitter, for wirelessly sending the ultrasound data to the external recorder, inside the capsule. This thesis highlights research towards the development of the CUS device, which, once developed, could be a revolutionary product for diagnosis of diseases in the GI tract, in particular the small intestine. Even though the development of the CUS device is a collaborative research project involving several students, in this thesis I demonstrate and share aspects of the research onto which I have contributed. In this thesis, I first discuss the system-level optimization of the CUS device through image simulations. Next, I highlight the transducer array fabrication process and the characterization results. Moreover, I demonstrate preliminary imaging results of the CUS device through wire and small bowel phantoms. Lastly, I share an integration scheme for the transducer array to increase patient safety. The research presented in this thesis for the design and development of the CUS device can be used to produce other wearable, disposable, and wireless-based medical devices to improve healthcare.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2019; ©2019 |
| Publication date | 2019; 2019 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Qureshi, Farah |
|---|---|
| Degree supervisor | Khuri-Yakub, Butrus T, 1948- |
| Thesis advisor | Khuri-Yakub, Butrus T, 1948- |
| Thesis advisor | Arbabian, Amin |
| Thesis advisor | Dahl, Jeremy J, 1976- |
| Thesis advisor | Pelc, Norbert J |
| Degree committee member | Arbabian, Amin |
| Degree committee member | Dahl, Jeremy J, 1976- |
| Degree committee member | Pelc, Norbert J |
| Associated with | Stanford University, Department of Bioengineering. |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Farah Qureshi. |
|---|---|
| Note | Submitted to the Department of Bioengineering. |
| Thesis | Thesis Ph.D. Stanford University 2019. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2019 by Farah Qureshi
Also listed in
Loading usage metrics...