Biomechanics of impact injuries and sensory perception of human skin
Abstract/Contents
- Abstract
- The biomechanical behavior of skin is critical for performing its functions of protecting from physical and thermal damage, facilitating sensorial perception, regulating body temperature, and preventing loss of moisture. However, injury to the skin can hinder it from protecting the individual and performing its functions. This is particularly true for fragment impact injuries as they increase the likelihood of infection and can exacerbate scarring. Unfortunately, there is a poor understanding of the damage processes involved in dynamic fragment impacts and their dependency on the impact angle, impact energy, and fragment characteristics including shape, volume, contact friction, and orientation. This paucity of knowledge presents a challenge in designing personal protective equipment intended to reduce these injuries. The focus of this thesis dissertation is to elucidate the damage mechanisms involved in cutaneous fragment impact injuries, demonstrate the influence of fragment and impact parameters on the injury mechanism and damage sequence, analyze the body's anatomical vulnerability to different types of impact injuries, for the goal of designing fragmentation resistant PPE that mitigate these injuries. The dissertation also focuses on developing a correlation between the strain state of the dermal-epidermal junction (DEJ) due to external stimuli and individuals' perception of tightness. Both topics utilize computational approaches to provide a mechanical analysis of the skin's response. A high-fidelity dynamic mechanics-driven model for cutaneous injuries was developed and used to analyze the mechanics behind single-projectile cutaneous injuries. This analysis was expanded upon using a multi-driven modeling approach involving numerical approaches and machine learning algorithms to predict multi-projectile full body cutaneous impact injuries. A structurally and topographically accurate 3D computational model of human skin was also developed to derive the strain state at the DEJ. The models provide a quantitative framework for understanding the detailed mechanisms of cutaneous damage, analyzing the influence of impact parameters on injury severity, acting as a basis for the design of PPE, and assessing the correlation between skin's mechanical response and firing rates associated with tactile perception.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2023; ©2023 |
| Publication date | 2023; 2023 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | ElSafty, Omar Ahmed ElSayed Rashad |
|---|---|
| Degree supervisor | Dauskardt, R. H. (Reinhold H.) |
| Degree supervisor | Okamura, Allison |
| Thesis advisor | Dauskardt, R. H. (Reinhold H.) |
| Thesis advisor | Okamura, Allison |
| Thesis advisor | DeSimone, Joseph M |
| Degree committee member | DeSimone, Joseph M |
| Associated with | Stanford University, School of Engineering |
| Associated with | Stanford University, Department of Mechanical Engineering |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Omar ElSafty. |
|---|---|
| Note | Submitted to the Department of Mechanical Engineering. |
| Thesis | Thesis Ph.D. Stanford University 2023. |
| Location | https://purl.stanford.edu/gr447vn1305 |
Access conditions
- Copyright
- © 2023 by Omar Ahmed ElSayed Rashad ElSafty
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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