Using Deep Learning-based Natural Language Processing to Identify Reasons for Statin Nonuse in Patients with Atherosclerotic Cardiovascular Disease

Placeholder Show Content

Abstract/Contents

Abstract
Statins conclusively decrease mortality in atherosclerotic cardiovascular disease (ASCVD), the leading cause of death worldwide, and are strongly recommended by guidelines. However, real world statin use and persistence remain low, resulting in excess mortality. Identifying reasons for statin nonuse at scale across health systems is crucial to develop targeted interventions to improve statin use. We developed and validated a deep learning-based natural language processing (NLP) approach (Clinical Bidirectional Encoder Representations from Transformers [BERT]) to classify statin nonuse and reasons for statin nonuse using unstructured EHR data from a diverse healthcare system.

Description

Type of resource software, multimedia, text
Date created October 28, 2021
Date modified November 1, 2021; November 1, 2021; December 16, 2021; December 5, 2022
Publication date October 28, 2021

Creators/Contributors

Author Sarraju, Ashish ORCiD icon https://orcid.org/0000-0003-1649-2110 (unverified)
Author Coquet, Jean ORCiD icon https://orcid.org/0000-0002-7008-6925 (unverified)
Author Chan, Antonia ORCiD icon https://orcid.org/0000-0002-7496-9581 (unverified)
Author Ngo, Summer ORCiD icon https://orcid.org/0000-0002-7434-4143 (unverified)
Author Hernandez-Boussard, Tina ORCiD icon https://orcid.org/0000-0001-6553-3455 (unverified)
Author Rodriguez, Fatima ORCiD icon https://orcid.org/0000-0002-5226-0723 (unverified)

Subjects

Subject Natural language processing (Computer science)
Subject Medicine > Research
Subject Medical records
Subject Machine learning
Subject Statins (Cardiovascular agents)
Genre Software/code
Genre Code
Genre Computer program

Bibliographic information

Access conditions

Use and reproduction
User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
License
This work is licensed under a Creative Commons Attribution Non Commercial No Derivatives 4.0 International license (CC BY-NC-ND).

Preferred citation

Preferred citation
Sarraju, A. and Coquet, J. (2021). Using Deep Learning-based Natural Language Processing to Identify Reasons for Statin Nonuse in Patients with Atherosclerotic Cardiovascular Disease. Stanford Digital Repository. Available at https://purl.stanford.edu/gn923yy3398

Collection

Contact information

Also listed in

Loading usage metrics...