Exploring the complexity of pathway-level evolution
Abstract/Contents
- Abstract
- This thesis explores how genes evolve together as integrated systems. In Chapter 1, I present conceptual background on the field of complexity and its relevance to this topic. Chapter 2 discusses theoretical work analyzing expected levels of divergence and polymorphism in the simple case of a linear metabolic pathway. Chapters 3 through 5 are gene-specific evolutionary studies in which I analyze the glycolytic enzymes phosphofructokinase, aldolase, and enolase in molecular functional terms. These gene-specific studies will contribute to a forthcoming empirical analysis of glycolysis at the pathway level.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2014 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Longo, Mark D |
|---|---|
| Associated with | Stanford University, Department of Biology. |
| Primary advisor | Watt, Ward B |
| Thesis advisor | Watt, Ward B |
| Thesis advisor | Feldman, Marcus W |
| Thesis advisor | Fraser, Hunter B |
| Advisor | Feldman, Marcus W |
| Advisor | Fraser, Hunter B |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Mark D. Longo. |
|---|---|
| Note | Submitted to the Department of Biology. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2014. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2014 by Mark Denison Longo
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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