Scanning SQUID microscopy of magnetic cells
Abstract/Contents
- Abstract
- Scanning Superconducting Quantum Interference Device (SQUID) microscopy is a minimally invasive tool normally used to study magnetic fields in condensed matter systems. We apply the techniques of scanning SQUID microscopy to biological samples that exhibit strong magnetic properties. These biological samples are part of a larger interdepartmental project to produce magnetically labeled stem cells for use as tracers in MRI. Using our SQUID magnetometers, we hope to better characterize individual cells so that their growth can be optimized for use as contrast agents. This thesis is divided into two major parts. The first concerns the problem of fitting the dipoles measured with the SQUID magnetometer to extract their dipole moments. We determine that the most desirable way to determine the magnetic moment of a SQUID measured dipole is to fit two superconducting vortex images to the dipole data. The second describes preliminary experiments in which we measure individual magnetic cells using scanning SQUID microscopy. We find that, in the two types of cells measured, the magnetic moment per cell as determined by Quantum Designs Magnetic Property Measurement System (MPMS) measurements is higher than that determined by scanning SQUID microscopy. We speculate that the reason for this is that scanning SQUID is a low field technique, and so the magnetic moments of the many individual magnetic particles do not line up in the same direction to produce a large overall magnetic moment as they do in the high field environment of an MPMS.
Description
| Type of resource | text |
|---|---|
| Date created | June 19, 2013 |
Creators/Contributors
| Author | Dwyer, Bo |
|---|---|
| Degree granting institution | Stanford University, Department of Physics |
| Primary advisor | Moler, Kathryn A. |
| Advisor | Osgood, Brad |
Subjects
| Subject | SQUID |
|---|---|
| Subject | microscopy |
| Subject | magnet |
| Subject | magnetic |
| Subject | cell |
| Genre | Thesis |
Bibliographic information
Access conditions
- Use and reproduction
- User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
Preferred citation
- Preferred Citation
- Dwyer, Bo. (2013). Scanning SQUID microscopy of magnetic cells. Stanford Digital Repository. Available at: http://purl.stanford.edu/gh325bb5942
Collection
Undergraduate Theses, Department of Physics
View other items in this collection in SearchWorksContact information
- Contact
- bodwyer@stanford.edu
Also listed in
Loading usage metrics...