Some problems in quantitative genetics and modifier theory
Abstract/Contents
- Abstract
- The dissertation includes two parts and is divided into five chapters. The first part (chapters 1-3) involves rigorous analyses of some important quantitative genetic problems with related methodologies. The problems we study can be roughly divided into three categories: genetic nurturing analysis (chapter 1), heritability analysis (chapter 1-3) and the apportionment of human diversity (chapter 3). The methodological tools we use for genetic nurturing analysis and heritability analysis are mainly from traditional population genetics, gene-culture coevolution theory, and modern causal analysis, which is introduced in detail in chapter 1. Chapter 2 gives a more detailed review of the historical background of the issue of heritability and connects that with the latest researches. Chapter 3 forms a systematic review of Lewontin's lifetime contribution in human genetics and addresses some of the related disputes and misunderstandings. The second part (chapters 4-5) deals with some problems in modifier theory, with a focus on the Reduction Principle (chapter 4) and the mode of transmission (chapter 5). Chapter 4 extends the traditional modifier theory and studies whether the Reduction Principle still holds in a more general context, i.e. the null modifier case, where the leading eigenvalue of the dynamical system is 1, or when there can be a stable cycle . Chapter 5 models different structural assumptions about preferential oblique transmission and traces the corresponding evolutionary dynamics.
Description
| Type of resource | text |
|---|---|
| Form | electronic resource; remote; computer; online resource |
| Extent | 1 online resource. |
| Place | California |
| Place | [Stanford, California] |
| Publisher | [Stanford University] |
| Copyright date | 2022; ©2022 |
| Publication date | 2022; 2022 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Author | Shen, Hao, active 2022 |
|---|---|
| Degree supervisor | Feldman, Marcus W |
| Thesis advisor | Feldman, Marcus W |
| Thesis advisor | Rosenberg, Noah |
| Thesis advisor | Tuljapurkar, Shripad, 1951- |
| Degree committee member | Rosenberg, Noah |
| Degree committee member | Tuljapurkar, Shripad, 1951- |
| Associated with | Stanford University, Department of Biology |
Subjects
| Genre | Theses |
|---|---|
| Genre | Text |
Bibliographic information
| Statement of responsibility | Hao Shen. |
|---|---|
| Note | Submitted to the Department of Biology. |
| Thesis | Thesis Ph.D. Stanford University 2022. |
| Location | https://purl.stanford.edu/gd191yt3654 |
Access conditions
- Copyright
- © 2022 by Hao Shen
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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