HIV Care: Advanced Injection System for Viscous Medications
Abstract/Contents
- Abstract
- The rise of high-viscosity injectables presents a huge opportunity in terms of reducing the day-to-day burden of disease for patients – substituting a daily pill for a yearly injection. But it also presents a unique engineering challenge; creating enough pressure to force these medicines through a standard needle is unaddressed by present auto-injectors and standard syringes. We have designed a solution that uses stored energy to effectively create high injection pressures with minimal force required from the user. Specifically, our system uses a standard 900psi CO2 cartridge to drive a pneumatic ram which actuates the plunger in an ISO 13926-1 drug cartridge. The user controls the input to a regulator, so the force they provide is directly related to the force at the output. We have fabricated a fully functional and tightly integrated prototype completely from the ground up, the tests of which even exceeded our anticipated performance. We are able to inject a high viscosity medicine in less than 8 seconds, and do so over six times per CO2 cartridge. Additionally, our design is highly reusable and interfaces with only standard parts, from gas cartridge to pen needle. As such, we believe this concept is extremely refined and suitable for deployment in helping accelerate the adoption and validation of high-viscosity medicines and we look forward to seeing where our corporate partner takes this project.
Description
| Type of resource | text |
|---|---|
| Publication date | March 25, 2024; 2024 |
Creators/Contributors
| Author | Sanchez, Maria |
|---|---|
| Author | Schoeller, Carl |
| Author | Sternfels, Samantha |
| Author | Stone, Diego |
Subjects
| Subject | Viscous injection |
|---|---|
| Genre | Text |
| Genre | Report |
Bibliographic information
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- User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
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- This work is licensed under a Creative Commons Attribution Non Commercial 4.0 International license (CC BY-NC).
Preferred citation
- Preferred citation
- Sanchez, M., Schoeller, C., Sternfels, S., and Stone, D. (2024). HIV Care: Advanced Injection System for Viscous Medications. Stanford Digital Repository. Available at https://purl.stanford.edu/fr724wj2031. https://doi.org/10.25740/fr724wj2031.
Collection
ME170 Mechanical Engineering Design
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