Characterization and therapeutic modulation of mesenchymal and myeloid lineages

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Abstract/Contents

Abstract
Fibrosis and regeneration are intimately connected. While fibrotic processes create nonfunctional tissue through the deposition of connective tissue, regenerative processes have the potential to generate new functional tissue. In this manner, efforts to better understand and potentially inhibit fibrosis should be complemented by regenerative approaches. In the first half of this dissertation, mechanisms and targeted inhibition of fibrosis are investigated primarily in the context of mesenchymal lineages. Regenerative approaches focused around cell-based therapies are then explored in the second half of this dissertation.

Description

Type of resource text
Form electronic; electronic resource; remote
Extent 1 online resource.
Publication date 2016
Issuance monographic
Language English

Creators/Contributors

Associated with Walmsley, Graham G
Associated with Stanford University, Department of Regenerative Medicine and Stem Cell Biology.
Primary advisor Longaker, Michael T
Primary advisor Weissman, Irving L
Thesis advisor Longaker, Michael T
Thesis advisor Weissman, Irving L
Thesis advisor Lorenz, H. Peter
Thesis advisor Wu, Joseph Ching-Ming, 1971-
Advisor Lorenz, H. Peter
Advisor Wu, Joseph Ching-Ming, 1971-

Subjects

Genre Theses

Bibliographic information

Statement of responsibility Graham G. Walmsley.
Note Submitted to the Department of Regenerative Medicine and Stem Cell Biology.
Thesis Thesis (Ph.D.)--Stanford University, 2016.
Location electronic resource

Access conditions

Copyright
© 2016 by Graham Gordon Walmsley
License
This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).

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