Towards clinically viable neural prostheses through innovations in neuroscience, decoders, and interfaces

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Abstract/Contents

Abstract
Millions of people in the United States live with paralysis due to spinal cord injury or neurological diseases. The motor impairment limits the patients' independence and in some cases the ability to communicate. Brain-computer interfaces (BCIs) translate signals from the brain into useful control signals, manipulating end-effectors such as computer cursors or robotic arms. BCIs can help restore lost motor capabilities and improve the quality of life for people with paralysis. Intracortical BCIs (iBCIs) have shown promising results in clinical trials, making them the prime candidate as an assistive device for people with severe paralysis, such as tetraplegia. However, for most applications iBCIs need further improvements to be suitable for clinical use. In this dissertation, I aimed to advance the main three components of the iBCI system: the neural interface, the user estimation decoding algorithm, and the user interface. I advanced the three components using multidisciplinary tools from neuroscience, statistics, and engineering. I believe that the studies which comprise this dissertation are a step forward towards the goal of clinical viability of iBCIs.

Description

Type of resource text
Form electronic resource; remote; computer; online resource
Extent 1 online resource.
Place California
Place [Stanford, California]
Publisher [Stanford University]
Copyright date 2018; ©2018
Publication date 2018; 2018
Issuance monographic
Language English

Creators/Contributors

Author Even Chen, Nir
Degree supervisor Shenoy, Krishna V. (Krishna Vaughn)
Thesis advisor Shenoy, Krishna V. (Krishna Vaughn)
Thesis advisor Goldsmith, Andrea, 1964-
Thesis advisor Okamura, Allison
Degree committee member Goldsmith, Andrea, 1964-
Degree committee member Okamura, Allison
Associated with Stanford University, Department of Electrical Engineering.

Subjects

Genre Theses
Genre Text

Bibliographic information

Statement of responsibility Nir Even-Chen.
Note Submitted to the Department of Electrical Engineering.
Thesis Thesis Ph.D. Stanford University 2018.
Location electronic resource

Access conditions

Copyright
© 2018 by Nir Even Chen
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

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