RNA structural regulation of reverse transcription initiation in HIV
Abstract/Contents
- Abstract
- The process of reverse transcription in HIV is a crucial early step in the viral replication cycle and must take place before infection is complete. During this process, the viral single-stranded RNA genome is reverse transcribed into double-stranded DNA for incorporation into the host cell genome. HIV drug treatments that inhibit reverse transcription have been highly successful in treating and preventing infection. Understanding how this process is regulated on a molecular level is crucial for understanding how reverse transcription defects prevent viral replication. This work presents a series of biochemical and biophysical studies on the macromolecular components involved in regulating reverse transcription initiation in HIV.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2018 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Coey, Aaron Thomas |
|---|---|
| Associated with | Stanford University, Department of Biophysics. |
| Primary advisor | Puglisi, Joseph D |
| Thesis advisor | Puglisi, Joseph D |
| Thesis advisor | Bryant, Zev David |
| Thesis advisor | Kirkegaard, Karla |
| Thesis advisor | Puglisi, Elisabetta |
| Advisor | Bryant, Zev David |
| Advisor | Kirkegaard, Karla |
| Advisor | Puglisi, Elisabetta |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Aaron Thomas Coey. |
|---|---|
| Note | Submitted to the Department of Biophysics. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2018. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2018 by Aaron Thomas Coey
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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