Malaria Susceptibility Loci Identified in the Diversity Outbred Mice Population Supplemental Data

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Abstract/Contents

Abstract
The Diversity Outbred (DO) mouse population is a panel of genetically unique outbred individuals with high levels of genetic variation. This affords an opportunity to perform experiments in a well-established animal model while taking advantage of the wide range of natural genetic diversity. Here, we promote this unique mouse resource for studies in disease dynamics because it allows for genetic examination of mechanisms in mice exhibiting distinct pathologies during each stage of infection. This approach is based on quantitative trait locus mapping: identifying specific genome regions associated with phenotypic variance in traits of interest.

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Type of resource software, multimedia
Date created [ca. 2020]

Creators/Contributors

Author Kirosingh, Adam
Author Gupta, Avni
Author Chevee, Victoria
Author Lissner, Michelle
Author Davis, Nicole
Author Cumnock, Katherine
Principal investigator Schneider, David

Subjects

Subject Malaria
Subject Plasmodium chabaudi
Subject infection
Subject dynamics
Subject disease
Subject space
Genre Dataset

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License
This work is licensed under a Creative Commons Attribution 3.0 Unported license (CC BY).

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