Thermodynamic Optimization of Retinal Photocoagulation Surgery: Computational Model with Experimental Verification

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Abstract/Contents

Abstract
Current safety considerations in retinal laser photocoagulation limit the exposure duration to a minimum of 20 ms per pulse. By numerical thermal modeling verified by in vivo experiments with 22 Dutch Belted rabbits, we demonstrate that this procedure can be rendered safe at pulse durations as short as 10 ms by spatial or temporal profile shaping of the laser beam. A combined spatio-temporal modulation may further decrease the minimal duration to 5 ms. Along with decreasing operation time, this increase of speed is expected to decrease the heat diffusion into the inner retina and choroid, therefore reducing the pain and discomfort for the patient, as well as decreasing collateral damage to the inner retina.

Description

Type of resource text
Date created 2010

Creators/Contributors

Author Brown, Jefferson
Primary advisor Palankar, Daniel
Advisor Church, Sarah
Department Stanford University, Department of Physics

Subjects

Subject retinal photocoagulation
Genre Thesis

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User agrees that, where applicable, content will not be used to identify or to otherwise infringe the privacy or confidentiality rights of individuals. Content distributed via the Stanford Digital Repository may be subject to additional license and use restrictions applied by the depositor.
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

Preferred citation

Preferred Citation
Brown, Jefferson (2010). Thermodynamic optimization of retinal photocoagulation surgery: Computational model with experimental verification. Stanford Digital Repository. Available at http://purl.stanford.edu/bz017bq7668.

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Undergraduate Theses, Department of Physics

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