Efficient storage of and in DNA

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Abstract/Contents

Abstract
The last decade has witnessed staggering improvements in DNA sequencing technologies, leading to the emergence of new frontiers in genomics and medical research. Low-cost DNA sequencing has led to multiple large scale sequencing initiatives such as the Thousand Genomes Project and the Million Veterans Project leading to a huge surge in the amount of genomic data being generated. This deluge of information has motivated the development of compression techniques for genomic data. The advances in genomic sequencing and synthesis technologies have also opened avenues for research into the potential for using DNA for storage of digital data. This thesis studies two related problems: compression techniques for efficient storage of genomic sequencing data, and error-correction for storing digital data in DNA. Both of these problems utilize special properties of the DNA sequencing process in the algorithmic design. We start with a brief introduction to the genomic sequencing pipeline. We then look at the problems of genomic data compression and storage of digital data in DNA in detail, analyzing both the theoretical aspects and practical algorithmic designs

Description

Type of resource text
Form electronic resource; remote; computer; online resource
Extent 1 online resource
Place California
Place [Stanford, California]
Publisher [Stanford University]
Copyright date 2020; ©2020
Publication date 2020; 2020
Issuance monographic
Language English

Creators/Contributors

Author Tatwawadi, Kedar Shriram
Degree supervisor Weissman, Tsachy
Thesis advisor Weissman, Tsachy
Thesis advisor Özgür, Ayfer
Thesis advisor Wootters, Mary
Degree committee member Özgür, Ayfer
Degree committee member Wootters, Mary
Associated with Stanford University, Department of Electrical Engineering.

Subjects

Genre Theses
Genre Text

Bibliographic information

Statement of responsibility Kedar Shriram Tatwawadi
Note Submitted to the Department of Electrical Engineering
Thesis Thesis Ph.D. Stanford University 2020
Location electronic resource

Access conditions

Copyright
© 2020 by Kedar Shriram Tatwawadi
License
This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).

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