Quantitative measures of gait and reaching in toddlers born preterm with very-low birth-weight
Abstract/Contents
- Abstract
- This dissertation aims to quantitatively analyze functional lower- and upper-extremity movement in toddlers born preterm with very-low birth-weight (VLBW). Children born preterm with VLBW have increased risk of motor impairment, and early identification of impairment guides treatment to improve long-term function. Temporal-spatial parameters were quantified and analyzed in the context of neurodevelopment for two functional tasks: gait and reaching. 81 VLBW (≤1500 g) preterm (≤32 weeks) and 43 typically-developing (TD) toddlers successfully completed motor assessments at 18-22 months of age, adjusted for prematurity. Neurodevelopment of VLBW preterm participants was assessed with Bayley Scales of Infant Development-3rd Edition (BSID-III) motor composite, gross motor, and fine motor scores. Differences in temporal-spatial gait were found between lower-scoring preterm toddlers and TD toddlers, and BSID-III motor scores correlated with gait in preterm children. These differences were quantified in the Toddle Temporal-spatial Deviation Index (Toddle TDI), an index quantifying toddler gait deviation from typical. The Toddle TDI demonstrated sensitivity and specificity to gross motor function, and has potential as an easily-administered, revealing clinical and research gait metric. A new method for measuring temporal-spatial reach parameters with inertial sensors showed good agreement with the current gold standard of 3D marker-based motion capture. Using this method, preterm toddlers demonstrated substantial differences in temporal-spatial reach compared to TD toddlers, and evidence indicated several reach parameters were revealing of function and may be useful as a clinical assessment.
Description
| Type of resource | text |
|---|---|
| Form | electronic; electronic resource; remote |
| Extent | 1 online resource. |
| Publication date | 2016 |
| Issuance | monographic |
| Language | English |
Creators/Contributors
| Associated with | Cahill-Rowley, Katelyn | |
|---|---|---|
| Associated with | Stanford University, Department of Bioengineering. | |
| Primary advisor | Delp, Scott | |
| Primary advisor | Rose, Jessica | |
| Thesis advisor | Delp, Scott | |
| Thesis advisor | Rose, Jessica | |
| Thesis advisor | Gold, Garry E | |
| Advisor | Gold, Garry E |
Subjects
| Genre | Theses |
|---|
Bibliographic information
| Statement of responsibility | Katelyn Cahill-Rowley. |
|---|---|
| Note | Submitted to the Department of Bioengineering. |
| Thesis | Thesis (Ph.D.)--Stanford University, 2016. |
| Location | electronic resource |
Access conditions
- Copyright
- © 2016 by Katelyn Christine Cahill-Rowley
- License
- This work is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported license (CC BY-NC).
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